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Human variant of scavenger receptor BI (R174C) exhibits impaired cholesterol transport functions
HDL and its primary receptor, scavenger receptor class B type I (SR-BI), work together to promote the clearance of excess plasma cholesterol, thereby protecting against atherosclerosis. Human variants of SR-BI have been identified in patients with high HDL-cholesterol levels, and at least one varian...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985710/ https://www.ncbi.nlm.nih.gov/pubmed/33577783 http://dx.doi.org/10.1016/j.jlr.2021.100045 |