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Human variant of scavenger receptor BI (R174C) exhibits impaired cholesterol transport functions

HDL and its primary receptor, scavenger receptor class B type I (SR-BI), work together to promote the clearance of excess plasma cholesterol, thereby protecting against atherosclerosis. Human variants of SR-BI have been identified in patients with high HDL-cholesterol levels, and at least one varian...

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Detalles Bibliográficos
Autores principales:	May, Sarah C., Dron, Jacqueline S., Hegele, Robert A., Sahoo, Daisy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985710/ https://www.ncbi.nlm.nih.gov/pubmed/33577783 http://dx.doi.org/10.1016/j.jlr.2021.100045

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