Tracking Reactions of Asymmetric Organo‐Osmium Transfer Hydrogenation Catalysts in Cancer Cells

Most metallodrugs are prodrugs that can undergo ligand exchange and redox reactions in biological media. Here we have investigated the cellular stability of the anticancer complex [Os(II)[(η(6)‐p‐cymene)(RR/SS‐MePh‐DPEN)] [1] (MePh‐DPEN=tosyl‐diphenylethylenediamine) which catalyses the enantioselec...

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Detalles Bibliográficos
Autores principales: Bolitho, Elizabeth M., Coverdale, James P. C., Bridgewater, Hannah E., Clarkson, Guy J., Quinn, Paul D., Sanchez‐Cano, Carlos, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985874/
https://www.ncbi.nlm.nih.gov/pubmed/33590607
http://dx.doi.org/10.1002/anie.202016456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985874/
https://www.ncbi.nlm.nih.gov/pubmed/33590607
http://dx.doi.org/10.1002/anie.202016456

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