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SIRT6-specific inhibitor OSS-128167 exacerbates diabetic cardiomyopathy by aggravating inflammation and oxidative stress

Diabetic cardiomyopathy (DCM) is a serious complication of diabetes, which importantly contributes to the increased mortality of patients with diabetes. The development of DCM is accompanied by numerous pathological mechanisms, including oxidative stress and chronic inflammation. Accordingly, the pr...

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Detalles Bibliográficos
Autores principales: Huang, Yibo, Zhang, Junkai, Xu, Dongdong, Peng, Yu, Jin, Yuan, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986000/
https://www.ncbi.nlm.nih.gov/pubmed/33760202
http://dx.doi.org/10.3892/mmr.2021.12006