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SLIDR and SLOPPR: flexible identification of spliced leader trans-splicing and prediction of eukaryotic operons from RNA-Seq data

BACKGROUND: Spliced leader (SL) trans-splicing replaces the 5′ end of pre-mRNAs with the spliced leader, an exon derived from a specialised non-coding RNA originating from elsewhere in the genome. This process is essential for resolving polycistronic pre-mRNAs produced by eukaryotic operons into mon...

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Detalles Bibliográficos
Autores principales: Wenzel, Marius A., Müller, Berndt, Pettitt, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986045/
https://www.ncbi.nlm.nih.gov/pubmed/33752599
http://dx.doi.org/10.1186/s12859-021-04009-7