Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts

Conflicts between the replication and transcription machineries have profound effects on chromosome duplication, genome organization, and evolution across species. Head-on conflicts (lagging-strand genes) are significantly more detrimental than codirectional conflicts (leading-strand genes). The fun...

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Detalles Bibliográficos
Autores principales: Lang, Kevin S., Merrikh, Houra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986047/
https://www.ncbi.nlm.nih.gov/pubmed/33657379
http://dx.doi.org/10.1016/j.celrep.2021.108797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986047/
https://www.ncbi.nlm.nih.gov/pubmed/33657379
http://dx.doi.org/10.1016/j.celrep.2021.108797

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