Light‐Activated Electron Transfer and Catalytic Mechanism of Carnitine Oxidation by Rieske‐Type Oxygenase from Human Microbiota

Oxidation of quaternary ammonium substrate, carnitine by non‐heme iron containing Acinetobacter baumannii (Ab) oxygenase CntA/reductase CntB is implicated in the onset of human cardiovascular disease. Herein, we develop a blue‐light (365 nm) activation of NADH coupled to electron paramagnetic resona...

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Detalles Bibliográficos
Autores principales: Shanmugam, Muralidharan, Quareshy, Mussa, Cameron, Alexander D., Bugg, Timothy D. H., Chen, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986066/
https://www.ncbi.nlm.nih.gov/pubmed/33180358
http://dx.doi.org/10.1002/anie.202012381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986066/
https://www.ncbi.nlm.nih.gov/pubmed/33180358
http://dx.doi.org/10.1002/anie.202012381

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