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Light‐Activated Electron Transfer and Catalytic Mechanism of Carnitine Oxidation by Rieske‐Type Oxygenase from Human Microbiota
Oxidation of quaternary ammonium substrate, carnitine by non‐heme iron containing Acinetobacter baumannii (Ab) oxygenase CntA/reductase CntB is implicated in the onset of human cardiovascular disease. Herein, we develop a blue‐light (365 nm) activation of NADH coupled to electron paramagnetic resona...
Autores principales: | Shanmugam, Muralidharan, Quareshy, Mussa, Cameron, Alexander D., Bugg, Timothy D. H., Chen, Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986066/ https://www.ncbi.nlm.nih.gov/pubmed/33180358 http://dx.doi.org/10.1002/anie.202012381 |
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