Interaction with Ribosomal Proteins Accompanies Stress Induction of the Anticancer Metallodrug BOLD‐100/KP1339 in the Endoplasmic Reticulum

The ruthenium‐based anticancer agent BOLD‐100/KP1339 has shown promising results in several in vitro and in vivo tumour models as well as in early clinical trials. However, its mode of action remains to be fully elucidated. Recent evidence identified stress induction in the endoplasmic reticulum (ER...

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Detalles Bibliográficos
Autores principales: Neuditschko, Benjamin, Legin, Anton A., Baier, Dina, Schintlmeister, Arno, Reipert, Siegfried, Wagner, Michael, Keppler, Bernhard K., Berger, Walter, Meier‐Menches, Samuel M., Gerner, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986094/
https://www.ncbi.nlm.nih.gov/pubmed/33369073
http://dx.doi.org/10.1002/anie.202015962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986094/
https://www.ncbi.nlm.nih.gov/pubmed/33369073
http://dx.doi.org/10.1002/anie.202015962

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