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Hydrogen sulfide‐loaded microbubbles combined with ultrasound mediate thrombolysis and simultaneously mitigate ischemia‐reperfusion injury in a rat hindlimb model

BACKGROUND: Thromboembolism and subsequent ischemia/reperfusion injury (IRI) remain major clinical challenges. OBJECTIVES: To investigate whether hydrogen sulfide (H(2)S)‐loaded microbubbles (hs‐Mbs) combined with ultrasound (US) radiation (hs‐Mbs+US) dissolve thrombi and simultaneously alleviate ti...

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Detalles Bibliográficos
Autores principales: Zhong, Jiayuan, Sun, Yili, Han, Yuan, Chen, Xiaoqiang, Li, Hairui, Ma, Yusheng, Lai, Yanxian, Wei, Guoquan, He, Xiang, Li, Mengsha, Liao, Wangjun, Liao, Yulin, Cao, Shiping, Bin, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986145/
https://www.ncbi.nlm.nih.gov/pubmed/32979007
http://dx.doi.org/10.1111/jth.15110