Cellular Fucosylation Inhibitors Based on Fluorinated Fucose‐1‐phosphates

Fucosylation of glycans impacts a myriad of physiological and pathological processes. Inhibition of fucose expression emerges as a potential therapeutic avenue for example in cancer, inflammation, and infection. In this study, we found that protected 2‐fluorofucose 1‐phosphate efficiently inhibits c...

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Detalles Bibliográficos
Autores principales: Pijnenborg, Johan F. A., Visser, Eline A., Noga, Marek, Rossing, Emiel, Veizaj, Raisa, Lefeber, Dirk J., Büll, Christian, Boltje, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986151/
https://www.ncbi.nlm.nih.gov/pubmed/33336886
http://dx.doi.org/10.1002/chem.202005359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986151/
https://www.ncbi.nlm.nih.gov/pubmed/33336886
http://dx.doi.org/10.1002/chem.202005359

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