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Cellular Fucosylation Inhibitors Based on Fluorinated Fucose‐1‐phosphates
Fucosylation of glycans impacts a myriad of physiological and pathological processes. Inhibition of fucose expression emerges as a potential therapeutic avenue for example in cancer, inflammation, and infection. In this study, we found that protected 2‐fluorofucose 1‐phosphate efficiently inhibits c...
Autores principales: | Pijnenborg, Johan F. A., Visser, Eline A., Noga, Marek, Rossing, Emiel, Veizaj, Raisa, Lefeber, Dirk J., Büll, Christian, Boltje, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986151/ https://www.ncbi.nlm.nih.gov/pubmed/33336886 http://dx.doi.org/10.1002/chem.202005359 |
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