Population Pharmacokinetics of Tofacitinib in Patients With Moderate to Severe Ulcerative Colitis

Tofacitinib is an oral, small molecule Janus kinase inhibitor for the treatment of ulcerative colitis (UC). We characterized tofacitinib pharmacokinetics in patients with moderate to severe UC, and the effects of covariates on variability in pharmacokinetic parameter estimates. Data were pooled from...

Descripción completa

Detalles Bibliográficos
Autores principales: Vong, Camille, Martin, Steven W., Deng, Chenhui, Xie, Rujia, Ito, Kaori, Su, Chinyu, Sandborn, William J., Mukherjee, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986169/
https://www.ncbi.nlm.nih.gov/pubmed/33513294
http://dx.doi.org/10.1002/cpdd.899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986169/
https://www.ncbi.nlm.nih.gov/pubmed/33513294
http://dx.doi.org/10.1002/cpdd.899

Ejemplares similares