A Ligand Selection Strategy Identifies Chemical Probes Targeting the Proteases of SARS‐CoV‐2

Activity‐based probes are valuable tools for chemical biology. However, finding probes that specifically target the active site of an enzyme remains a challenging task. Herein, we present a ligand selection strategy that allows to rapidly tailor electrophilic probes to a target of choice and showcas...

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Detalles Bibliográficos
Autores principales: Peñalver, Lilian, Schmid, Philipp, Szamosvári, Dávid, Schildknecht, Stefan, Globisch, Christoph, Sawade, Kevin, Peter, Christine, Böttcher, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986205/
https://www.ncbi.nlm.nih.gov/pubmed/33350010
http://dx.doi.org/10.1002/anie.202016113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986205/
https://www.ncbi.nlm.nih.gov/pubmed/33350010
http://dx.doi.org/10.1002/anie.202016113

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