Kif3a deletion prevents primary cilia assembly on oligodendrocyte progenitor cells, reduces oligodendrogenesis and impairs fine motor function

Primary cilia are small microtubule‐based organelles capable of transducing signals from growth factor receptors embedded in the cilia membrane. Developmentally, oligodendrocyte progenitor cells (OPCs) express genes associated with primary cilia assembly, disassembly, and signaling, however, the imp...

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Detalles Bibliográficos
Autores principales: Cullen, Carlie L., O'Rourke, Megan, Beasley, Shannon J., Auderset, Loic, Zhen, Yilan, Pepper, Renee E., Gasperini, Robert, Young, Kaylene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986221/
https://www.ncbi.nlm.nih.gov/pubmed/33368703
http://dx.doi.org/10.1002/glia.23957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986221/
https://www.ncbi.nlm.nih.gov/pubmed/33368703
http://dx.doi.org/10.1002/glia.23957

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