The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo

KEY POINTS: Reduced vitamin D receptor (VDR) expression prompts skeletal muscle atrophy. Atrophy occurs through catabolic processes, namely the induction of autophagy, while anabolism remains unchanged. In response to VDR‐knockdown mitochondrial function and related gene‐set expression is impaired....

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Detalles Bibliográficos
Autores principales: Bass, Joseph J., Kazi, Abid A., Deane, Colleen S., Nakhuda, Asif, Ashcroft, Stephen P., Brook, Matthew S., Wilkinson, Daniel J., Phillips, Bethan E., Philp, Andrew, Tarum, Janelle, Kadi, Fawzi, Andersen, Ditte, Garcia, Amadeo Muñoz, Smith, Ken, Gallagher, Iain J., Szewczyk, Nathaniel J., Cleasby, Mark E., Atherton, Philip J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Muscle
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986223/
https://www.ncbi.nlm.nih.gov/pubmed/33258480
http://dx.doi.org/10.1113/JP280652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986223/
https://www.ncbi.nlm.nih.gov/pubmed/33258480
http://dx.doi.org/10.1113/JP280652

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