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Nonlinear ridge regression improves cell-type-specific differential expression analysis
BACKGROUND: Epigenome-wide association studies (EWAS) and differential gene expression analyses are generally performed on tissue samples, which consist of multiple cell types. Cell-type-specific effects of a trait, such as disease, on the omics expression are of interest but difficult or costly to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986289/ https://www.ncbi.nlm.nih.gov/pubmed/33752591 http://dx.doi.org/10.1186/s12859-021-03982-3 |