Mechanochemical Solvent‐Free Catalytic C−H Methylation

The mechanochemical, solvent‐free, highly regioselective, rhodium‐catalyzed C−H methylation of (hetero)arenes is reported. The reaction shows excellent functional‐group compatibility and is demonstrated to work for the late‐stage C−H methylation of biologically active compounds. The method requires...

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Detalles Bibliográficos
Autores principales: Ni, Shengjun, Hribersek, Matic, Baddigam, Swarna K., Ingner, Fredric J. L., Orthaber, Andreas, Gates, Paul J., Pilarski, Lukasz T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986365/
https://www.ncbi.nlm.nih.gov/pubmed/33031646
http://dx.doi.org/10.1002/anie.202010202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986365/
https://www.ncbi.nlm.nih.gov/pubmed/33031646
http://dx.doi.org/10.1002/anie.202010202

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