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Mechanochemical Solvent‐Free Catalytic C−H Methylation
The mechanochemical, solvent‐free, highly regioselective, rhodium‐catalyzed C−H methylation of (hetero)arenes is reported. The reaction shows excellent functional‐group compatibility and is demonstrated to work for the late‐stage C−H methylation of biologically active compounds. The method requires...
Autores principales: | Ni, Shengjun, Hribersek, Matic, Baddigam, Swarna K., Ingner, Fredric J. L., Orthaber, Andreas, Gates, Paul J., Pilarski, Lukasz T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986365/ https://www.ncbi.nlm.nih.gov/pubmed/33031646 http://dx.doi.org/10.1002/anie.202010202 |
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