Enantioselective Cleavage of Cyclobutanols Through Ir‐Catalyzed C−C Bond Activation: Mechanistic and Synthetic Aspects

The Ir‐catalyzed conversion of prochiral tert‐cyclobutanols to β‐methyl‐substituted ketones proceeds under comparably mild conditions in toluene (45–110 °C) and is particularly suited for the enantioselective desymmetrization of β‐oxy‐substituted substrates to give products with a quaternary chirali...

Descripción completa

Detalles Bibliográficos
Autores principales: Ratsch, Friederike, Strache, Joss Pepe, Schlundt, Waldemar, Neudörfl, Jörg‐Martin, Adler, Andreas, Aziz, Sarwar, Goldfuss, Bernd, Schmalz, Hans‐Günther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986405/
https://www.ncbi.nlm.nih.gov/pubmed/33314360
http://dx.doi.org/10.1002/chem.202004843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986405/
https://www.ncbi.nlm.nih.gov/pubmed/33314360
http://dx.doi.org/10.1002/chem.202004843

Ejemplares similares