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Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer’s pathophysiology

Although abnormal accumulation of amyloid in the brain is an early biomarker of Alzheimer’s disease (AD), wide variation in cognitive trajectories during life can be seen in the setting of brain amyloidosis, ranging from maintenance of normal function to progression to dementia. It is widely presume...

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Detalles Bibliográficos
Autores principales: Ramanan, Vijay K., Lesnick, Timothy G., Przybelski, Scott A., Heckman, Michael G., Knopman, David S., Graff-Radford, Jonathan, Lowe, Val J., Machulda, Mary M., Mielke, Michelle M., Jack, Clifford R., Petersen, Ronald C., Ross, Owen A., Vemuri, Prashanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986461/
https://www.ncbi.nlm.nih.gov/pubmed/33757599
http://dx.doi.org/10.1186/s40478-021-01154-1