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Specific depletion of resident microglia in the early stage of stroke reduces cerebral ischemic damage

BACKGROUND: Ischemia can induce rapid activation of microglia in the brain. As key immunocompetent cells, reactive microglia play an important role in pathological development of ischemic stroke. However, the role of activated microglia during the development of ischemia remains controversial. Thus,...

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Detalles Bibliográficos
Autores principales: Li, Ting, Zhao, Jin, Xie, Wenguang, Yuan, Wanru, Guo, Jing, Pang, Shengru, Gan, Wen-Biao, Gómez-Nicola, Diego, Zhang, Shengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986495/
https://www.ncbi.nlm.nih.gov/pubmed/33757565
http://dx.doi.org/10.1186/s12974-021-02127-w