Bioprocess performance analysis of novel methanol-independent promoters for recombinant protein production with Pichia pastoris

BACKGROUND: Pichia pastoris is a powerful and broadly used host for recombinant protein production (RPP), where past bioprocess performance has often been directed with the methanol regulated AOX1 promoter (P(AOX1)), and the constitutive GAP promoter (P(GAP)). Since promoters play a crucial role in...

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Detalles Bibliográficos
Autores principales: Garrigós-Martínez, Javier, Vuoristo, Kiira, Nieto-Taype, Miguel Angel, Tähtiharju, Juha, Uusitalo, Jaana, Tukiainen, Pauliina, Schmid, Christian, Tolstorukov, Ilya, Madden, Knut, Penttilä, Merja, Montesinos-Seguí, José Luis, Valero, Francisco, Glieder, Anton, Garcia-Ortega, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986505/
https://www.ncbi.nlm.nih.gov/pubmed/33757505
http://dx.doi.org/10.1186/s12934-021-01564-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986505/
https://www.ncbi.nlm.nih.gov/pubmed/33757505
http://dx.doi.org/10.1186/s12934-021-01564-9

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