Functions for Retinoic Acid-Related Orphan Receptor Alpha (RORα) in the Activation of Macrophages During Lipopolysaccharide-Induced Septic Shock

The transcription factor Related Orphan Receptor Alpha (RORα) plays an important role in regulating circadian rhythm, inflammation, metabolism and cellular development. Herein we show that in the absence of functional RORα in mice there is reduced susceptibility to LPS-induced endotoxic shock, with...

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Detalles Bibliográficos
Autores principales: Hams, Emily, Roberts, Joseph, Bermingham, Rachel, Fallon, Padraic G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986717/
https://www.ncbi.nlm.nih.gov/pubmed/33767712
http://dx.doi.org/10.3389/fimmu.2021.647329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986717/
https://www.ncbi.nlm.nih.gov/pubmed/33767712
http://dx.doi.org/10.3389/fimmu.2021.647329

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