Klotho Regulates Epithelial-to-Mesenchymal Transition In Vitro via Wnt/β-Catenin Pathway and Attenuates Chronic Allograft Dysfunction in a Rat Renal Transplant Model

BACKGROUND: Klotho deficiency has been implicated in various kidney diseases and has been associated with renal fibrosis. However, the role of Klotho in renal allograft fibrosis still remains undetermined. MATERIAL/METHODS: A 24-week-old rat renal transplant model with chronic allograft dysfunction...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Jun, Lu, Pei, Shao, Xue-Feng, Jiang, Ting, Liu, Feng, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986726/
https://www.ncbi.nlm.nih.gov/pubmed/33737505
http://dx.doi.org/10.12659/AOT.930066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986726/
https://www.ncbi.nlm.nih.gov/pubmed/33737505
http://dx.doi.org/10.12659/AOT.930066

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