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Klotho Regulates Epithelial-to-Mesenchymal Transition In Vitro via Wnt/β-Catenin Pathway and Attenuates Chronic Allograft Dysfunction in a Rat Renal Transplant Model
BACKGROUND: Klotho deficiency has been implicated in various kidney diseases and has been associated with renal fibrosis. However, the role of Klotho in renal allograft fibrosis still remains undetermined. MATERIAL/METHODS: A 24-week-old rat renal transplant model with chronic allograft dysfunction...
Autores principales: | Li, Xiao-Jun, Lu, Pei, Shao, Xue-Feng, Jiang, Ting, Liu, Feng, Li, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986726/ https://www.ncbi.nlm.nih.gov/pubmed/33737505 http://dx.doi.org/10.12659/AOT.930066 |
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