Induced hepatic stellate cell integrin, α8β1, enhances cellular contractility and TGFβ activity in liver fibrosis

No effective therapy exists for fatal fibrosis. New therapeutic targets are needed for hepatic fibrosis because the incidence keeps increasing. The activation and differentiation of fibroblasts into myofibroblasts that causes excessive matrix deposition is central to fibrosis. Here, we investigated...

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Detalles Bibliográficos
Autores principales: Nishimichi, Norihisa, Tsujino, Kazuyuki, Kanno, Keishi, Sentani, Kazuhiro, Kobayashi, Tsuyoshi, Chayama, Kazuaki, Sheppard, Dean, Yokosaki, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986747/
https://www.ncbi.nlm.nih.gov/pubmed/33433924
http://dx.doi.org/10.1002/path.5618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986747/
https://www.ncbi.nlm.nih.gov/pubmed/33433924
http://dx.doi.org/10.1002/path.5618

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