A Chiral Pentafluorinated Isopropyl Group via Iodine(I)/(III) Catalysis

An I(I)/(III) catalysis strategy to construct an enantioenriched fluorinated isostere of the (i)Pr group is reported. The difluorination of readily accessible α‐CF(3)‐styrenes is enabled by the in situ generation of a chiral ArIF(2) species to forge a stereocentre with the substituents F, CH(2)F and...

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Detalles Bibliográficos
Autores principales: Meyer, Stephanie, Häfliger, Joel, Schäfer, Michael, Molloy, John J., Daniliuc, Constantin G., Gilmour, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986799/
https://www.ncbi.nlm.nih.gov/pubmed/33427355
http://dx.doi.org/10.1002/anie.202015946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986799/
https://www.ncbi.nlm.nih.gov/pubmed/33427355
http://dx.doi.org/10.1002/anie.202015946

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