Cargando…

ABCA7 and the altered lipidostasis hypothesis of Alzheimer's disease

We propose the altered lipidostasis hypothesis of Alzheimer's disease (AD). It holds that vulnerable neurons of the entorhinal region generate a neurodegenerative lipid during normal function, adenosine triphosphate–binding cassette transporter subfamily A member 7 (ABCA7) protects from AD path...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyssenko, Nicholas N., Praticò, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986801/
https://www.ncbi.nlm.nih.gov/pubmed/33336544
http://dx.doi.org/10.1002/alz.12220