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Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation

Major histocompatibility class I (MHC I) molecules bind peptides derived from a cell's expressed genes and then transport and display this antigenic information on the cell surface. This allows CD8 T cells to identify pathological cells that are synthesizing abnormal proteins, such as cancers t...

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Detalles Bibliográficos
Autores principales: Dhatchinamoorthy, Karthik, Colbert, Jeff D., Rock, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986854/
https://www.ncbi.nlm.nih.gov/pubmed/33767702
http://dx.doi.org/10.3389/fimmu.2021.636568