Cargando…

Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation

Major histocompatibility class I (MHC I) molecules bind peptides derived from a cell's expressed genes and then transport and display this antigenic information on the cell surface. This allows CD8 T cells to identify pathological cells that are synthesizing abnormal proteins, such as cancers t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dhatchinamoorthy, Karthik, Colbert, Jeff D., Rock, Kenneth L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7986854/ https://www.ncbi.nlm.nih.gov/pubmed/33767702 http://dx.doi.org/10.3389/fimmu.2021.636568

Ejemplares similares

MHC Class I Cross-Presentation by Dendritic Cells Counteracts Viral Immune Evasion
por: Nopora, Katrin, et al.
Publicado: (2012)

Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer
por: Demel, Uta M., et al.
Publicado: (2022)

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation
por: Wieczorek, Marek, et al.
Publicado: (2017)

The Role of Insulin-Regulated Aminopeptidase in MHC Class I Antigen Presentation
por: Saveanu, Loredana, et al.
Publicado: (2012)

MHC Class II Auto-Antigen Presentation is Unconventional
por: Sadegh-Nasseri, Scheherazade, et al.
Publicado: (2015)

Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets
por: Gutiérrez-Martínez, Enric, et al.
Publicado: (2015)

An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
por: Burr, Marian L., et al.
Publicado: (2019)

Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation
por: Colbert, Jeff D., et al.
Publicado: (2022)

Endogenous Antigen Presentation of MHC Class II Epitopes through Non-Autophagic Pathways
por: Leung, Carol S. K.
Publicado: (2015)

Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I
por: Leddy, Owen, et al.
Publicado: (2023)

Antigen Processing for MHC Class II Presentation via Autophagy
por: Münz, Christian
Publicado: (2012)

Endocytic Recycling of MHC Class I Molecules in Non-professional Antigen Presenting and Dendritic Cells
por: Montealegre, Sebastian, et al.
Publicado: (2019)

Chaperone function in antigen presentation by MHC class I molecules—tapasin in the PLC and TAPBPR beyond
por: Margulies, David H., et al.
Publicado: (2023)

Mechanistic diversity in MHC class I antigen recognition
por: Barbosa, Camila R. R., et al.
Publicado: (2021)

HLA-DO and Its Role in MHC Class II Antigen Presentation
por: Poluektov, Yuri O., et al.
Publicado: (2013)

Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation
por: Baptista, Antonio P, et al.
Publicado: (2014)

Acute Pharmacologic Degradation of a Stable Antigen Enhances Its Direct Presentation on MHC Class I Molecules
por: Moser, Sarah C., et al.
Publicado: (2018)

Alternative Antigen Processing for MHC Class I: Multiple Roads Lead to Rome
por: Oliveira, Cláudia C., et al.
Publicado: (2015)

MHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance?
por: Walter, W, et al.
Publicado: (2000)

Organizing MHC Class II Presentation
por: Fooksman, David R.
Publicado: (2014)

Involvement of autophagy in MHC class I antigen presentation
por: Øynebråten, Inger
Publicado: (2020)

Macroautophagy in Endogenous Processing of Self- and Pathogen-Derived Antigens for MHC Class II Presentation
por: Duraes, Fernanda V., et al.
Publicado: (2015)

Palladium-Induced Temporal Internalization of MHC Class I Contributes to T Cell-Mediated Antigenicity
por: Ito, Koyu, et al.
Publicado: (2021)

Loss of antigen-presenting molecules (MHC class I and TAP-1) in lung cancer.
por: Korkolopoulou, P., et al.
Publicado: (1996)

Intracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-Presentation
por: Adiko, Aimé Cézaire, et al.
Publicado: (2015)

Understanding MHC Class I Presentation of Viral Antigens by Human Dendritic Cells as a Basis for Rational Design of Therapeutic Vaccines
por: van Montfoort, Nadine, et al.
Publicado: (2014)

Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I
por: Horrevorts, Sophie K., et al.
Publicado: (2018)

Antigen Processing by Macroautophagy for MHC Presentation
por: Münz, Christian
Publicado: (2011)

Antigen Presentation by MHC-Dressed Cells
por: Nakayama, Masafumi
Publicado: (2015)

Epithelial MHC Class II Expression and Its Role in Antigen Presentation in the Gastrointestinal and Respiratory Tracts
por: Wosen, Jonathan E., et al.
Publicado: (2018)

Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation
por: Zhang, Biying, et al.
Publicado: (2023)

MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis
por: Harrington, Em P, et al.
Publicado: (2023)

The Macroautophagy Machinery in MHC Restricted Antigen Presentation
por: Münz, Christian
Publicado: (2021)

Variations in MHC class I antigen presentation and immunopeptidome selection pathways
por: Zaitouna, Anita J., et al.
Publicado: (2020)

Role of MHC class I pathways in Mycobacterium tuberculosis antigen presentation
por: Witt, Karolina D.
Publicado: (2023)

The structure of songbird MHC class I reveals antigen binding that is flexible at the N-terminus and static at the C-terminus
por: Eltschkner, Sandra, et al.
Publicado: (2023)

Corneal Epithelial Cells Exhibit Myeloid Characteristics and Present Antigen via MHC Class II
por: Royer, Derek J., et al.
Publicado: (2018)

A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules
por: Boulanger, Denise S. M., et al.
Publicado: (2018)

Adaptations of Natural Killer Cells to Self-MHC Class I
por: Bessoles, Stéphanie, et al.
Publicado: (2014)

Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility
por: Ayres, Cory M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kur8hfgn1u4epa293kb80caibs