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Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response

The rapid spread of COVID-19 underscores the need for new treatments. Here we report that cannabidiol (CBD), a compound produced by the cannabis plant, inhibits SARS-CoV-2 infection. CBD and its metabolite, 7-OH-CBD, but not congeneric cannabinoids, potently block SARS-CoV-2 replication in lung epit...

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Detalles Bibliográficos
Autores principales: Nguyen, Long Chi, Yang, Dongbo, Nicolaescu, Vlad, Best, Thomas J., Ohtsuki, Takashi, Chen, Shao-Nong, Friesen, J. Brent, Drayman, Nir, Mohamed, Adil, Dann, Christopher, Silva, Diane, Gula, Haley, Jones, Krysten A., Millis, J. Michael, Dickinson, Bryan C., Tay, Savaş, Oakes, Scott A., Pauli, Guido F., Meltzer, David O., Randall, Glenn, Rosner, Marsha Rich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987002/
https://www.ncbi.nlm.nih.gov/pubmed/33758843
http://dx.doi.org/10.1101/2021.03.10.432967