Yeast surface display-based identification of ACE2 mutations that modulate SARS-CoV-2 spike binding across multiple mammalian species

Understanding how SARS-CoV-2 interacts with different mammalian angiotensin-converting enzyme II (ACE2) cell entry receptors elucidates determinants of virus transmission and facilitates development of vaccines for humans and animals. Yeast display-based directed evolution identified conserved ACE2...

Descripción completa

Detalles Bibliográficos
Autores principales: Heinzelman, Pete, Greenhalgh, Jonathan C., Romero, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987019/
https://www.ncbi.nlm.nih.gov/pubmed/33758860
http://dx.doi.org/10.1101/2021.03.16.435705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987019/
https://www.ncbi.nlm.nih.gov/pubmed/33758860
http://dx.doi.org/10.1101/2021.03.16.435705

Ejemplares similares