Cargando…

Yeast surface display-based identification of ACE2 mutations that modulate SARS-CoV-2 spike binding across multiple mammalian species

Understanding how SARS-CoV-2 interacts with different mammalian angiotensin-converting enzyme II (ACE2) cell entry receptors elucidates determinants of virus transmission and facilitates development of vaccines for humans and animals. Yeast display-based directed evolution identified conserved ACE2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heinzelman, Pete, Greenhalgh, Jonathan C., Romero, Philip A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987019/ https://www.ncbi.nlm.nih.gov/pubmed/33758860 http://dx.doi.org/10.1101/2021.03.16.435705

Ejemplares similares

Discovery of human ACE2 variants with altered recognition by the SARS-CoV-2 spike protein
por: Heinzelman, Pete, et al.
Publicado: (2020)

Discovery of human ACE2 variants with altered recognition by the SARS-CoV-2 spike protein
por: Heinzelman, Pete, et al.
Publicado: (2021)

De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions
por: Heinzelman, Pete, et al.
Publicado: (2019)

Machine Learning Approach Effectively Predicts Binding Between SARS-CoV-2 Spike and ACE2 Across Mammalian Species — Worldwide, 2021
por: Ma, Yue, et al.
Publicado: (2021)

Analysis of ACE2 Gene-Encoded Proteins Across Mammalian Species
por: Cao, Ying, et al.
Publicado: (2020)

Directed evolution of angiotensin‐converting enzyme 2 peptidase activity profiles for therapeutic applications
por: Heinzelman, Pete, et al.
Publicado: (2023)

Harnessing coronavirus spike proteins' binding affinity to ACE2 receptor through a novel baculovirus surface display system
por: Wang, Lin, et al.
Publicado: (2022)

Rapid characterization of spike variants via mammalian cell surface display
por: Javanmardi, Kamyab, et al.
Publicado: (2021)

In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin
por: Piplani, Sakshi, et al.
Publicado: (2021)

Spike residue 403 affects binding of coronavirus spikes to human ACE2
por: Zech, Fabian, et al.
Publicado: (2021)

Author Correction: In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin
por: Piplani, Sakshi, et al.
Publicado: (2021)

Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection
por: Luan, Junwen, et al.
Publicado: (2020)

SARS-CoV-2 spike and ACE2 entanglement-like binding
por: Pregnolato, Massimo, et al.
Publicado: (2023)

The ACE2-binding interface of SARS-CoV-2 Spike inherently deflects immune recognition
por: Hattori, Takamitsu, et al.
Publicado: (2020)

Variations in cell-surface ACE2 levels alter direct binding of SARS-CoV-2 Spike protein and viral infectivity: Implications for measuring Spike protein interactions with animal ACE2 orthologs
por: Kazemi, Soheila, et al.
Publicado: (2021)

Variations in Cell Surface ACE2 Levels Alter Direct Binding of SARS-CoV-2 Spike Protein and Viral Infectivity: Implications for Measuring Spike Protein Interactions with Animal ACE2 Orthologs
por: Kazemi, Soheila, et al.
Publicado: (2022)

The ACE2-binding Interface of SARS-CoV-2 Spike Inherently Deflects Immune Recognition
por: Hattori, Takamitsu, et al.
Publicado: (2021)

Structural analysis of COVID-19 spike protein in recognizing the ACE2 receptor of different mammalian species and its susceptibility to viral infection
por: Koley, Tirthankar, et al.
Publicado: (2021)

The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins
por: Conceicao, Carina, et al.
Publicado: (2020)

Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2
por: Chan, Kui K., et al.
Publicado: (2020)

The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2
por: Procko, Erik
Publicado: (2020)

Revealing the Mechanism of SARS-CoV-2 Spike Protein Binding With ACE2
Publicado: (2020)

Mechanism and evolution of human ACE2 binding by SARS-CoV-2 spike
por: Wrobel, Antoni G.
Publicado: (2023)

Biophysical properties of the isolated spike protein binding helix of human ACE2
por: Das, Anirban, et al.
Publicado: (2021)

Chloroquine and Hydroxychloroquine Interact Differently with ACE2 Domains Reported to Bind with the Coronavirus Spike Protein: Mediation by ACE2 Polymorphism
por: Badraoui, Riadh, et al.
Publicado: (2021)

Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike
por: Mehdipour, Ahmad Reza, et al.
Publicado: (2021)

Perturbation of ACE2 Structural Ensembles by SARS-CoV-2 Spike Protein Binding
por: Uyar, Arzu, et al.
Publicado: (2021)

SARS-CoV-2 spike binding to ACE2 is stronger and longer ranged with glycans
por: Huang, Yihan, et al.
Publicado: (2022)

Identifying Hotspots in Binding of SARS-CoV-2 Spike Glycoprotein and Human ACE2
por: Mendis, Jenny, et al.
Publicado: (2021)

SARS-COV-2 spike binding to ACE2 in living cells monitored by TR-FRET
por: Cecon, Erika, et al.
Publicado: (2022)

Modelling SARS-CoV-2 spike-protein mutation effects on ACE2 binding
por: Thakur, Shivani, et al.
Publicado: (2023)

Synthetic carbohydrate-binding agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2
por: Francesconi, Oscar, et al.
Publicado: (2022)

Display of receptor-binding domain of SARS-CoV-2 Spike protein variants on the Saccharomyces cerevisiae cell surface
por: Xing, Hongguan, et al.
Publicado: (2022)

Engaging the spikes: heparan sulfate facilitates SARS-CoV-2 spike protein binding to ACE2 and potentiates viral infection
por: Kalra, Rajkumar Singh, et al.
Publicado: (2021)

Phage Display-Derived Compounds Displace hACE2 from Its Complex with SARS-CoV-2 Spike Protein
por: Sevenich, Marc, et al.
Publicado: (2022)

Sphingosine prevents binding of SARS–CoV-2 spike to its cellular receptor ACE2
por: Edwards, Michael J., et al.
Publicado: (2020)

Dexamethasone inhibits SARS-CoV-2 spike pseudotyped virus viropexis by binding to ACE2
por: Zhang, Yongjing, et al.
Publicado: (2021)

ACE2-cytomimetic particles restrict SARS-Cov-2 spike protein binding to cellular targets
por: Strong, Thomas A., et al.
Publicado: (2021)

Plastic Antibodies Mimicking the ACE2 Receptor for Selective Binding of SARS‐CoV‐2 Spike
por: Batista, Alex D., et al.
Publicado: (2022)

Prediction of Residue-specific Contributions to Binding and Thermal Stability Using Yeast Surface Display
por: Ahmed, Shahbaz, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_onucd8ki66hcre21fb6th0n20m