Emodin Ameliorates Renal Damage and Podocyte Injury in a Rat Model of Diabetic Nephropathy via Regulating AMPK/mTOR-Mediated Autophagy Signaling Pathway

PURPOSE: The activation of autophagy has potential protective effect on diabetic nephropathy (DN) podocyte injury, and the AMPK/mTOR signaling pathway is an important regulatory pathway of autophagy. Emodin has been reported to effectively delay DN progression; however, the therapeutic mechanisms in...

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Detalles Bibliográficos
Autores principales: Liu, Hong, Wang, Quan, Shi, Ge, Yang, Wenqiang, Zhang, Yanmin, Chen, Weidong, Wan, Sheng, Xiong, Fei, Wang, Zengsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987270/
https://www.ncbi.nlm.nih.gov/pubmed/33776462
http://dx.doi.org/10.2147/DMSO.S299375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987270/
https://www.ncbi.nlm.nih.gov/pubmed/33776462
http://dx.doi.org/10.2147/DMSO.S299375

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