Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin

Channelrhodopsins (ChRs) are microbial light-gated ion channels utilized in optogenetics to control neural activity with light . Light absorption causes retinal chromophore isomerization and subsequent protein conformational changes visualized as optically distinguished intermediates, coupled with c...

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Detalles Bibliográficos
Autores principales: Oda, Kazumasa, Nomura, Takashi, Nakane, Takanori, Yamashita, Keitaro, Inoue, Keiichi, Ito, Shota, Vierock, Johannes, Hirata, Kunio, Maturana, Andrés D, Katayama, Kota, Ikuta, Tatsuya, Ishigami, Itsuki, Izume, Tamaki, Umeda, Rie, Eguma, Ryuun, Oishi, Satomi, Kasuya, Go, Kato, Takafumi, Kusakizako, Tsukasa, Shihoya, Wataru, Shimada, Hiroto, Takatsuji, Tomoyuki, Takemoto, Mizuki, Taniguchi, Reiya, Tomita, Atsuhiro, Nakamura, Ryoki, Fukuda, Masahiro, Miyauchi, Hirotake, Lee, Yongchan, Nango, Eriko, Tanaka, Rie, Tanaka, Tomoyuki, Sugahara, Michihiro, Kimura, Tetsunari, Shimamura, Tatsuro, Fujiwara, Takaaki, Yamanaka, Yasuaki, Owada, Shigeki, Joti, Yasumasa, Tono, Kensuke, Ishitani, Ryuichiro, Hayashi, Shigehiko, Kandori, Hideki, Hegemann, Peter, Iwata, So, Kubo, Minoru, Nishizawa, Tomohiro, Nureki, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987342/
https://www.ncbi.nlm.nih.gov/pubmed/33752801
http://dx.doi.org/10.7554/eLife.62389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987342/
https://www.ncbi.nlm.nih.gov/pubmed/33752801
http://dx.doi.org/10.7554/eLife.62389

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