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Agnuside Alleviates Synovitis and Fibrosis in Knee Osteoarthritis through the Inhibition of HIF-1α and NLRP3 Inflammasome

Increasing evidence has shown that NLRP3 inflammasome activation participates in chronic aseptic inflammation and is related to tissue fibrosis. Our last study also revealed the vital role of NLRP3 inflammasome, highly associated with tissue hypoxia, in the onset and development of knee osteoarthrit...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Li, Xiaochen, Zhang, Haosheng, Huang, Zhengquan, Zhang, Nongshan, Xing, Runlin, Wang, Peimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987448/
https://www.ncbi.nlm.nih.gov/pubmed/33814979
http://dx.doi.org/10.1155/2021/5534614