Cargando…

Agnuside Alleviates Synovitis and Fibrosis in Knee Osteoarthritis through the Inhibition of HIF-1α and NLRP3 Inflammasome

Increasing evidence has shown that NLRP3 inflammasome activation participates in chronic aseptic inflammation and is related to tissue fibrosis. Our last study also revealed the vital role of NLRP3 inflammasome, highly associated with tissue hypoxia, in the onset and development of knee osteoarthrit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Li, Li, Xiaochen, Zhang, Haosheng, Huang, Zhengquan, Zhang, Nongshan, Xing, Runlin, Wang, Peimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987448/ https://www.ncbi.nlm.nih.gov/pubmed/33814979 http://dx.doi.org/10.1155/2021/5534614

Ejemplares similares

Inhibition of Synovial Macrophage Pyroptosis Alleviates Synovitis and Fibrosis in Knee Osteoarthritis
por: Zhang, Li, et al.
Publicado: (2019)

Imperatorin alleviated NLR family pyrin domain-containing 3 inflammasome cascade-induced synovial fibrosis and synovitis in rats with knee osteoarthritis
por: Zhang, Haosheng, et al.
Publicado: (2021)

Vanillic Acid Reduces Pain-Related Behavior in Knee Osteoarthritis Rats Through the Inhibition of NLRP3 Inflammasome-Related Synovitis
por: Ma, Zhenyuan, et al.
Publicado: (2021)

Increased HIF-1α in Knee Osteoarthritis Aggravate Synovial Fibrosis via Fibroblast-Like Synoviocyte Pyroptosis
por: Zhang, Li, et al.
Publicado: (2019)

Sanse Powder Essential Oil Nanoemulsion Negatively Regulates TRPA1 by AMPK/mTOR Signaling in Synovitis: Knee Osteoarthritis Rat Model and Fibroblast-Like Synoviocyte Isolates
por: Li, Mingchao, et al.
Publicado: (2021)

Network Pharmacology Approach to Uncover the Mechanism Governing the Effect of Simiao Powder on Knee Osteoarthritis
por: Huang, Zhengquan, et al.
Publicado: (2020)

Chrysin Attenuates the NLRP3 Inflammasome Cascade to Reduce Synovitis and Pain in KOA Rats
por: Liao, Taiyang, et al.
Publicado: (2020)

MicroRNA-10a-3p Improves Cartilage Degeneration by Regulating CH25H-CYP7B1-RORα Mediated Cholesterol Metabolism in Knee Osteoarthritis Rats
por: Li, Xiaochen, et al.
Publicado: (2021)

Mechanism of NLRP3 inflammasome intervention for synovitis in knee osteoarthritis: A review of TCM intervention
por: Han, Xianfu, et al.
Publicado: (2023)

Synovial Fibrosis Involvement in Osteoarthritis
por: Zhang, Li, et al.
Publicado: (2021)

Targeting NLRP3 Inflammasome Alleviates Synovitis by Reducing Pyroptosis in Rats with Experimental Temporomandibular Joint Osteoarthritis
por: Xin, Yinzi, et al.
Publicado: (2022)

Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling
por: Ding, Liang, et al.
Publicado: (2023)

l-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway
por: Liao, Taiyang, et al.
Publicado: (2023)

Interventional effects of the direct application of “Sanse powder” on knee osteoarthritis in rats as determined from lipidomics via UPLC-Q-Exactive Orbitrap MS
por: Wu, Peng, et al.
Publicado: (2020)

Characteristics of sensory innervation in synovium of rats within different knee osteoarthritis models and the correlation between synovial fibrosis and hyperalgesia
por: Zhang, Li, et al.
Publicado: (2021)

Electroacupuncture Alleviates Osteoarthritis by Suppressing NLRP3 Inflammasome Activation in Guinea Pigs
por: Wang, Zhankui, et al.
Publicado: (2020)

Effect of Ultrasound-Enhanced Transdermal Drug Delivery Efficiency of Nanoparticles and Brucine
por: Zhang, Nongshan, et al.
Publicado: (2017)

Network Pharmacology Approach to Uncover the Mechanism Governing the Effect of Radix Achyranthis Bidentatae on Osteoarthritis
por: Zhang, Laigen, et al.
Publicado: (2020)

Electroacupuncture ameliorates knee osteoarthritis in rats via inhibiting NLRP3 inflammasome and reducing pyroptosis
por: Zhang, Wei, et al.
Publicado: (2023)

Interventional Efects of the Topical of “Sanse Powder” Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis
por: Liu, Zixiu, et al.
Publicado: (2021)

Relationship between the pyroptosis of fibroblast-like synoviocytes and HMGB1 secretion in knee osteoarthritis
por: Xiao, Yancheng, et al.
Publicado: (2021)

GCTOF-MS Combined LC-QTRAP-MS/MS Reveals Metabolic Difference Between Osteoarthritis and Osteoporotic Osteoarthritis and the Intervention Effect of Erxian Decoction
por: Ma, Zhenyuan, et al.
Publicado: (2022)

Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis
por: Zu, Yan, et al.
Publicado: (2019)

Remdesivir Alleviates Acute Kidney Injury by Inhibiting the Activation of NLRP3 Inflammasome
por: Yin, Liang, et al.
Publicado: (2021)

Validated HPLC method for identification and quantification of p-hydroxy benzoic acid and agnuside in Vitex negundo and Vitex trifolia
por: Shah, Sonal, et al.
Publicado: (2013)

Calycosin Alleviates Doxorubicin-Induced Cardiotoxicity and Pyroptosis by Inhibiting NLRP3 Inflammasome Activation
por: Zhang, Lei, et al.
Publicado: (2022)

Combination of magnesium ions and vitamin C alleviates synovitis and osteophyte formation in osteoarthritis of mice
por: Yao, Hao, et al.
Publicado: (2020)

Melatonin Alleviates Lipopolysaccharide-Induced Endometritis by Inhibiting the Activation of NLRP3 Inflammasome through Autophagy
por: Gao, Yujin, et al.
Publicado: (2023)

Synovitis Ointment Improved Knee Osteoarthritis by Suppressing SDF-1/CXCR4 Signaling Pathway
por: Zhang, Jin, et al.
Publicado: (2022)

Stabilization of HIF-1α alleviates osteoarthritis via enhancing mitophagy
por: Hu, Sunli, et al.
Publicado: (2020)

Dihydromyricetin alleviates Escherichia coli lipopolysaccharide-induced hepatic injury in chickens by inhibiting the NLRP3 inflammasome
por: Shi, Chenxi, et al.
Publicado: (2022)

The association between patellofemoral grind and synovitis in knee osteoarthritis: data from the osteoarthritis initiative
por: Deng, Hui, et al.
Publicado: (2023)

Saikosaponin d Alleviates Liver Fibrosis by Negatively Regulating the ROS/NLRP3 Inflammasome Through Activating the ERβ Pathway
por: Zhang, Kehui, et al.
Publicado: (2022)

Ketogenic diet ameliorates inflammation by inhibiting the NLRP3 inflammasome in osteoarthritis
por: Kong, Ganggang, et al.
Publicado: (2022)

NLRP3 Inflammasome and Inflammatory Diseases
por: Wang, Zheng, et al.
Publicado: (2020)

HIF1α-BNIP3-mediated mitophagy protects against renal fibrosis by decreasing ROS and inhibiting activation of the NLRP3 inflammasome
por: Li, Jialin, et al.
Publicado: (2023)

Tetramethylpyrazine alleviates acute kidney injury by inhibiting NLRP3/HIF-1α and apoptosis
por: Sun, Wangnan, et al.
Publicado: (2020)

Correlation between systemic markers of inflammation and local synovitis in knee osteoarthritis
por: Babaei, Mansour, et al.
Publicado: (2019)

The histopathological synovitis score is influenced by biopsy location in patients with knee osteoarthritis
por: Mussawy, Haider, et al.
Publicado: (2021)

Hyperbaric oxygen alleviates the activation of NLRP-3-inflammasomes in traumatic brain injury
por: Qian, Huihui, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_uleotusqutdmred8t8cl5dc1oi