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Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro

Acute and chronic liver inflammation is driven by cytokine and chemokine release from various cell types in the liver. Here, we report that the induction of inflammatory mediators is associated with a yet undescribed upregulation of the metalloproteinase ADAM8 in different murine hepatitis models. W...

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Detalles Bibliográficos
Autores principales: Awan, Tanzeela, Babendreyer, Aaron, Wozniak, Justyna, Alvi, Abid Mahmood, Sterzer, Viktor, Cook, Lena, Bartsch, Jörg W., Liedtke, Christian, Yildiz, Daniela, Ludwig, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987468/
https://www.ncbi.nlm.nih.gov/pubmed/33814981
http://dx.doi.org/10.1155/2021/6665028