Homocysteine-induced decrease in HUVEC cells’ resistance to oxidative stress is mediated by Akt-dependent changes in iron metabolism

PURPOSE: Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases and also promotes neuronal death in various neurodegenerative diseases. There is evidence that iron can mediate homocysteine (Hcy) toxicity. Thus, the aim of this study was to investigate the effect of Hcy on iro...

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Detalles Bibliográficos
Autores principales: Borkowska, Andzelika, Ziolkowski, Wieslaw, Kaczor, Katarzyna, Herman-Antosiewicz, Anna, Knap, Narcyz, Wronska, Agata, Antosiewicz, Jedrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987610/
https://www.ncbi.nlm.nih.gov/pubmed/32794021
http://dx.doi.org/10.1007/s00394-020-02360-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987610/
https://www.ncbi.nlm.nih.gov/pubmed/32794021
http://dx.doi.org/10.1007/s00394-020-02360-8

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