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Rational Design of Hyaluronic Acid-Based Copolymer-Mixed Micelle in Combination PD-L1 Immune Checkpoint Blockade for Enhanced Chemo-Immunotherapy of Melanoma

The application of combinational therapy breaks the limitation of monotherapy and achieves better clinical benefit for tumor therapy. Herein, a hyaluronic acid/Pluronic F68-based copolymer-mixed micelle was constructed for targeted delivery of chemotherapeutical agent docetaxel (PHDM) in combination...

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Detalles Bibliográficos
Autores principales: Zhou, Chaopei, Dong, Xiuxiu, Song, Chunxiang, Cui, Shuang, Chen, Tiantian, Zhang, Daji, Zhao, Xiuli, Yang, Chunrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987940/
https://www.ncbi.nlm.nih.gov/pubmed/33777920
http://dx.doi.org/10.3389/fbioe.2021.653417