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Translation error clusters induced by aminoglycoside antibiotics

Aminoglycoside antibiotics target the ribosome and induce mistranslation, yet which translation errors induce bacterial cell death is unclear. The analysis of cellular proteins by quantitative mass spectrometry shows that bactericidal aminoglycosides induce not only single translation errors, but al...

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Detalles Bibliográficos
Autores principales: Wohlgemuth, Ingo, Garofalo, Raffaella, Samatova, Ekaterina, Günenç, Aybeg Nafiz, Lenz, Christof, Urlaub, Henning, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987974/
https://www.ncbi.nlm.nih.gov/pubmed/33758186
http://dx.doi.org/10.1038/s41467-021-21942-6