Cargando…

Translation error clusters induced by aminoglycoside antibiotics

Aminoglycoside antibiotics target the ribosome and induce mistranslation, yet which translation errors induce bacterial cell death is unclear. The analysis of cellular proteins by quantitative mass spectrometry shows that bactericidal aminoglycosides induce not only single translation errors, but al...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wohlgemuth, Ingo, Garofalo, Raffaella, Samatova, Ekaterina, Günenç, Aybeg Nafiz, Lenz, Christof, Urlaub, Henning, Rodnina, Marina V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987974/ https://www.ncbi.nlm.nih.gov/pubmed/33758186 http://dx.doi.org/10.1038/s41467-021-21942-6

Ejemplares similares

Broad range of missense error frequencies in cellular proteins
por: Garofalo, Raffaella, et al.
Publicado: (2019)

Translational recoding: canonical translation mechanisms reinterpreted
por: Rodnina, Marina V, et al.
Publicado: (2020)

Studying macromolecular complex stoichiometries by peptide‐based mass spectrometry
por: Wohlgemuth, Ingo, et al.
Publicado: (2015)

Translational Control by Ribosome Pausing in Bacteria: How a Non-uniform Pace of Translation Affects Protein Production and Folding
por: Samatova, Ekaterina, et al.
Publicado: (2021)

Ribosome rearrangements at the onset of translational bypassing
por: Agirrezabala, Xabier, et al.
Publicado: (2017)

Cotranslational Folding of Proteins on the Ribosome
por: Liutkute, Marija, et al.
Publicado: (2020)

Essential structural elements in tRNA(Pro) for EF-P-mediated alleviation of translation stalling
por: Katoh, Takayuki, et al.
Publicado: (2016)

Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin
por: Parajuli, Narayan Prasad, et al.
Publicado: (2021)

Activities of the peptidyl transferase center of ribosomes lacking protein L27
por: Maracci, Cristina, et al.
Publicado: (2015)

Gradual compaction of the nascent peptide during cotranslational folding on the ribosome
por: Liutkute, Marija, et al.
Publicado: (2020)

A switch from α‐helical to β‐strand conformation during co‐translational protein folding
por: Agirrezabala, Xabier, et al.
Publicado: (2022)

Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs
por: Korniy, Natalia, et al.
Publicado: (2019)

Dynamics of ribosomes and release factors during translation termination in E. coli
por: Adio, Sarah, et al.
Publicado: (2018)

Ototoxicity of Non-aminoglycoside Antibiotics
por: Rybak, Leonard P., et al.
Publicado: (2021)

Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance
por: Korniy, Natalia, et al.
Publicado: (2019)

DNA-Aptamers Binding Aminoglycoside Antibiotics
por: Nikolaus, Nadia, et al.
Publicado: (2014)

Selective condensation of DNA by aminoglycoside antibiotics
por: Kopaczynska, M., et al.
Publicado: (2015)

Parallel pathways in the biosynthesis of aminoglycoside antibiotics
por: Yu, Yi, et al.
Publicado: (2017)

Aminoglycoside Antibiotics Inhibit Mycobacteriophage Infection
por: Jiang, Zheng, et al.
Publicado: (2020)

Conformational rearrangements upon start codon recognition in human 48S translation initiation complex
por: Yi, Sung-Hui, et al.
Publicado: (2022)

Review: Translational GTPases
por: Maracci, Cristina, et al.
Publicado: (2016)

Aminoglycoside antibiotics and autism: a speculative hypothesis
por: Manev, Radmila, et al.
Publicado: (2001)

The Supramolecular Self‐Assembly of Aminoglycoside Antibiotics and their Applications
por: Jadhav, Ratan W., et al.
Publicado: (2019)

The relationship between the structure and toxicity of aminoglycoside antibiotics
por: Jospe-Kaufman, Moriah, et al.
Publicado: (2020)

Laccase-Catalyzed Derivatization of Aminoglycoside Antibiotics and Glucosamine
por: Mikolasch, Annett, et al.
Publicado: (2022)

Long-range signalling in activation of the translational GTPase EF-Tu
por: Rodnina, Marina V
Publicado: (2009)

Roles of specific aminoglycoside–ribosome interactions in the inhibition of translation
por: Ying, Lanqing, et al.
Publicado: (2019)

Capture-SELEX: Selection of DNA Aptamers for Aminoglycoside Antibiotics
por: Stoltenburg, Regina, et al.
Publicado: (2012)

Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance
por: Shi, Kun, et al.
Publicado: (2013)

4′-O-substitutions determine selectivity of aminoglycoside antibiotics
por: Perez-Fernandez, Déborah, et al.
Publicado: (2014)

Potentiating aminoglycoside antibiotics to reduce their toxic side effects
por: Rosenberg, Christopher R., et al.
Publicado: (2020)

Advances in the Application of Aptamer Biosensors to the Detection of Aminoglycoside Antibiotics
por: Luan, Yunxia, et al.
Publicado: (2020)

Potential for the Development of a New Generation of Aminoglycoside Antibiotics
por: Tevyashova, A. N., et al.
Publicado: (2022)

Analysis of Aminoglycoside Antibiotics: A Challenge in Food Control
por: Nowacka-Kozak, Ewelina, et al.
Publicado: (2023)

Sequestosome 1 Is Part of the Interaction Network of VAPB
por: James, Christina, et al.
Publicado: (2021)

Antibiotic Combination Therapy: A Strategy to Overcome Bacterial Resistance to Aminoglycoside Antibiotics
por: Wang, Nuoyan, et al.
Publicado: (2022)

The ins and outs of translation
por: Clancy, Jennifer L, et al.
Publicado: (2007)

Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA
por: Andreeva, Irena, et al.
Publicado: (2018)

Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
por: Scheunemann, Ann E., et al.
Publicado: (2010)

Overcoming Aminoglycoside Enzymatic Resistance: Design of Novel Antibiotics and Inhibitors
por: Zárate, Sandra G., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_t6ei98ig6tdau8498hgngtac87