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Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis

Synthetic glucocorticoids (GCs), one of the most effective treatments for chronic inflammatory and autoimmune conditions in children, have adverse effects on the growing skeleton. GCs inhibit angiogenesis in growing bone, but the underlying mechanisms remain unclear. Here, we show that GC treatment...

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Detalles Bibliográficos
Autores principales: Liu, Xiaonan, Chai, Yu, Liu, Guanqiao, Su, Weiping, Guo, Qiaoyue, Lv, Xiao, Gao, Peisong, Yu, Bin, Ferbeyre, Gerardo, Cao, Xu, Wan, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987975/
https://www.ncbi.nlm.nih.gov/pubmed/33758201
http://dx.doi.org/10.1038/s41467-021-22131-1