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HiCancer: accurate and complete cancer genome phasing with Hi-C reads

Due to the high complexity of cancer genome, it is too difficult to generate complete cancer genome map which contains the sequence of every DNA molecule until now. Nevertheless, phasing each chromosome in cancer genome into two haplotypes according to germline mutations provides a suboptimal soluti...

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Detalles Bibliográficos
Autores principales: Pan, Weihua, Gong, Desheng, Sun, Da, Luo, Haohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987978/
https://www.ncbi.nlm.nih.gov/pubmed/33758310
http://dx.doi.org/10.1038/s41598-021-86104-6