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SIRT1 attenuates renal fibrosis by repressing HIF-2α
Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase belonging to class III histone deacetylases. Previous studies have shown that SIRT1 is involved in kidney physiology regulation and protects the kidney from various pathological factors. However, the underlying m...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987992/ https://www.ncbi.nlm.nih.gov/pubmed/33758176 http://dx.doi.org/10.1038/s41420-021-00443-x |