Cargando…
SIRT1 attenuates renal fibrosis by repressing HIF-2α
Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase belonging to class III histone deacetylases. Previous studies have shown that SIRT1 is involved in kidney physiology regulation and protects the kidney from various pathological factors. However, the underlying m...
Autores principales: | Li, Peipei, Liu, Yue, Qin, Xiaogang, Chen, Kairen, Wang, Ruiting, Yuan, Li, Chen, Xiaolan, Hao, Chuanming, Huang, Xinzhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987992/ https://www.ncbi.nlm.nih.gov/pubmed/33758176 http://dx.doi.org/10.1038/s41420-021-00443-x |
Ejemplares similares
-
Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD(+)/SIRT1 axis
por: Wu, Keke, et al.
Publicado: (2023) -
Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis
por: Xu, Xiao, et al.
Publicado: (2022) -
VHL-recruiting PROTAC attenuates renal fibrosis and preserves renal function via simultaneous degradation of Smad3 and stabilization of HIF-2α
por: Yang, Jiayi, et al.
Publicado: (2022) -
Hypoxia represses early responses of prostate and renal cancer cells to YM155 independent of HIF-1α and HIF-2α
por: Danielpour, David, et al.
Publicado: (2021) -
Profilin-1 suppresses tumorigenicity in pancreatic cancer through regulation of the SIRT3-HIF1α axis
por: Yao, Wantong, et al.
Publicado: (2014)