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SIRT1 attenuates renal fibrosis by repressing HIF-2α

Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase belonging to class III histone deacetylases. Previous studies have shown that SIRT1 is involved in kidney physiology regulation and protects the kidney from various pathological factors. However, the underlying m...

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Detalles Bibliográficos
Autores principales: Li, Peipei, Liu, Yue, Qin, Xiaogang, Chen, Kairen, Wang, Ruiting, Yuan, Li, Chen, Xiaolan, Hao, Chuanming, Huang, Xinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987992/
https://www.ncbi.nlm.nih.gov/pubmed/33758176
http://dx.doi.org/10.1038/s41420-021-00443-x

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