PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons

Recent evidence suggests neurogenesis is on-going throughout life but the relevance of these findings for neurodegenerative disorders such as Parkinson’s disease (PD) is poorly understood. Biallelic PINK1 mutations cause early onset, Mendelian inherited PD. We studied the effect of PINK1 deficiency...

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Detalles Bibliográficos
Autores principales: Brown, Sarah J., Boussaad, Ibrahim, Jarazo, Javier, Fitzgerald, Julia C., Antony, Paul, Keatinge, Marcus, Blechman, Janna, Schwamborn, Jens C., Krüger, Rejko, Placzek, Marysia, Bandmann, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988014/
https://www.ncbi.nlm.nih.gov/pubmed/33758225
http://dx.doi.org/10.1038/s41598-021-84278-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988014/
https://www.ncbi.nlm.nih.gov/pubmed/33758225
http://dx.doi.org/10.1038/s41598-021-84278-7

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