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PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons
Recent evidence suggests neurogenesis is on-going throughout life but the relevance of these findings for neurodegenerative disorders such as Parkinson’s disease (PD) is poorly understood. Biallelic PINK1 mutations cause early onset, Mendelian inherited PD. We studied the effect of PINK1 deficiency...
Autores principales: | Brown, Sarah J., Boussaad, Ibrahim, Jarazo, Javier, Fitzgerald, Julia C., Antony, Paul, Keatinge, Marcus, Blechman, Janna, Schwamborn, Jens C., Krüger, Rejko, Placzek, Marysia, Bandmann, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988014/ https://www.ncbi.nlm.nih.gov/pubmed/33758225 http://dx.doi.org/10.1038/s41598-021-84278-7 |
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