Characterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS

Liquid droplets of aggregation-prone proteins, which become hydrogels or form amyloid fibrils, are a potential target for drug discovery. In this study, we proposed an experiment-guided protocol for characterizing the design grammar of peptides that can regulate droplet formation and aggregation. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamagata, Kiyoto, Chiba, Rika, Kawahata, Ichiro, Iwaki, Nanako, Kanbayashi, Saori, Maeda, Kana, Takahashi, Hiroto, Hirano, Atsushi, Fukunaga, Koji, Ikeda, Keisuke, Kameda, Tomoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988016/
https://www.ncbi.nlm.nih.gov/pubmed/33758287
http://dx.doi.org/10.1038/s41598-021-86098-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988016/
https://www.ncbi.nlm.nih.gov/pubmed/33758287
http://dx.doi.org/10.1038/s41598-021-86098-1

Ejemplares similares